Name :
Active Recombinant Human FCGR2A Protein (R167) (Ala 36 – Ile 218), His & Avi-tagged, Biotinylated
Specification :
| Source : HEK293 | Species : Human | Tag : His & Avi | Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. | Bio-activity : Recombinant Human FCGR2A Protein (R167), His & Avi-tagged, Biotinylated captured on Biotin CAP- Series S Sensor Chip can bind Rituximab with an affinity constant of 2.15 μM as determined in a SPR assay (Biacore T200) (QC tested). | Molecular Mass : 24.0 kDa | Protein length : Ala 36 – Ile 218 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >95% as determined by SDS-PAGE. | Notes : Please avoid repeated freeze-thaw cycles. | Stability : No activity loss is observed after storage at:4-8 centigrade for 12 months in lyophilized state;-70 centigrade for 3 months under sterile conditions after reconstitution. | Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Information :
| Gene Name : FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) [ Homo sapiens ] | Official Symbol : FCGR2A | Synonyms : FCGR2A; CD32; CD32A; CDw32; IGFR2; fcRII-a; fc-gamma-RIIa; FCG2; FcGR; FCGR2; FCGR2A1; MGC23887; MGC30032; | Gene ID : 2212 | mRNA Refseq : NM_001136219 | Protein Refseq : NP_001129691 | MIM : 146790 | UniProt ID : P12318
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