Name :
Recombinant Human FCGR2B Protein, His-tagged
Specification :
| Description : The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : His | Form : Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.2 | Molecular Mass : 20.64kD | AA Sequence : TPAAPPKAVLKLEPQWINVLQEDSV TLTCRGTHSPESDSIQWFHNGNLIP THTQPSYRFKANNNDSGEYTCQTGQ TSLSDPVHLTVLSEWLVLQTPHLEF QEGETIVLRCHSWKDKPLVKVTFFQ NGKSKKFSRSDPNFSIPQANHSHSG DYHCTGNIGYTLYSSKPVTITVQAP VDHHHHHH | Endotoxin : Endotoxin level is | Purity : >95% as determined by SDS-PAGE and Coomassie blue staining | Concentration : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Information :
| Gene Name : FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) [ Homo sapiens ] | Official Symbol : FCGR2B | Synonyms : FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32) , FCG2, FCGR2; low affinity immunoglobulin gamma Fc region receptor II-b; CD32; CD32B; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; IgG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); FCG2; FCGR2; IGFR2; | Gene ID : 2213 | mRNA Refseq : NM_001002273 | Protein Refseq : NP_001002273 | MIM : 604590 | UniProt ID : P31994
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