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Name :
Active Recombinant Human FCGR3B protein, His & Avi-tagged, Biotinylated

Specification :
| Source : HEK293 | Species : Human | Tag : His & Avi | Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. | Bio-activity : Biotinylated Human CD16b (NA2), His,Avitag captured on Biotin CAP- Series S Sensor Chip can bind Rituximab with an affinity constant of 4.22 μM as determined in a SPR assay (Biacore T200). | Molecular Mass : The protein has a calculated MW of 24.5 kDa. The protein migrates as 37-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. | Protein Length : Gly 17 – Ser 200 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. | Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.Please avoid repeated freeze-thaw cycles.This product is stable after storage at:-20 centigrade to -70 centigrade for 12 months in lyophilized state;-70 centigrade for 3 months under sterile conditions after reconstitution. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information :
| Gene Name : FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) [ Homo sapiens ] | Official Symbol : FCGR3B | Synonyms : FCGR3B; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc fragment of IgG, low affinity IIIb, receptor for (CD16) , FCG3, FCGR3; low affinity immunoglobulin gamma Fc region receptor III-B; CD16; CD16b; fc-gamma RIII; fc-gamma RIIIb; fc-gamma RIII-beta; IgG Fc receptor III-1; Fc-gamma receptor IIIb (CD 16); Fc fragment of IgG, low affinity IIIb, receptor for (CD16); FCG3; FCGR3; FCR-10; FCRIII; FCRIIIb; | Gene ID : 2215 | mRNA Refseq : NM_000570 | Protein Refseq : NP_000561 | MIM : 610665 | UniProt ID : O75015

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors