Recombinant Human FES Protein, GST-tagged

Specification :
| Description : This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 116.16 kDa | AA Sequence : MGFSSELCSPQGHGVLQQMQEAELR LLEGMRKWMAQRVKSDREYAGLLHH MSLQDSGGQSRAISPDSPISQSWAE ITSQTEGLSRLLRQHAEDLNSGPLS KLSLLIRERQQLRKTYSEQWQQLQQ ELTKTHSQDIEKLKSQYRALARDSA QAKRKYQEASKDKDRDKAKDKYVRS LWKLFAHHNRYVLGVRAAQLHHQHH HQLLLPGLLRSLQDLHEEMACILKE ILQEYLEISSLVQDEVVAIHREMAA AAARIQPEAEYQGFLRQYGSAPDVP PCVTFDESLLEEGEPLEPGELQLNE LTVESVQHTLTSVTDELAVATEMVF RRQEMVTQLQQELRNEEENTHPRER VQLLGKRQVLQEALQGLQVALCSQA KLQAQQELLQTKLEHLGPGEPPPVL LLQDDRHSTSSSEQEREGGRTPTLE ILKSHISGIFRPKFSLPPPLQLIPE VQKPLHEQLWYHGAIPRAEVAELLV HSGDFLVRESQGKQEYVLSVLWDGL PRHFIIQSLDNLYRLEGEGFPSIPL LIDHLLSTQQPLTKKSGVVLHRAVP KDKWVLNHEDLVLGEQIGRGNFGEV FSGRLRADNTLVAVKSCRETLPPDL KAKFLQEARILKQYSHPNIVRLIGV CTQKQPIYIVMELVQGGDFLTFLRT EGARLRVKTLLQMVGDAAAGMEYLE SKCCIHRDLAARNCLVTEKNVLKIS DFGMSREEADGVYAASGGLRQVPVK WTAPEALNYGRYSSESDVWSFGILL WETFSLGASPYPNLSNQQTREFVEK GGRLPCPELCPDAVFRLMEQCWAYE PGQRPSFSTIYQELQSIRKRHR | Applications : Kinase AssayEnzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.