Recombinant Human FGR Protein, GST-tagged

Specification :
| Description : This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 85.9 kDa | AA Sequence : MGCVFCKKLEPVATAKEDAGLEGDF RSYGAADHYGPDPTKARPASSFAHI PNYSNFSSQAINPGFLDSGTIRGVS GIGVTLFIALYDYEARTEDDLTFTK GEKFHILNNTEGDWWEARSLSSGKT GCIPSNYVAPVDSIQAEEWYFGKIG RKDAERQLLSPGNPQGAFLIRESET TKGAYSLSIRDWDQTRGDHVKHYKI RKLDMGGYYITTRVQFNSVQELVQH YMEVNDGLCNLLIAPCTIMKPQTLG LAKDAWEISRSSITLERRLGTGCFG DVWLGTWNGSTKVAVKTLKPGTMSP KAFLEEAQVMKLLRHDKLVQLYAVV SEEPIYIVTEFMCHGSLLDFLKNPE GQDLRLPQLVDMAAQVAEGMAYMER MNYIHRDLRAANILVGERLACKIAD FGLARLIKDDEYNPCQGSKFPIKWT APEAALFGRFTIKSDVWSFGILLTE LITKGRIPYPGMNKREVLEQVEQGY HMPCPPGCPASLYEAMEQTWRLDPE ERPTFEYLQSFLEDYFTSAEPQYQP GDQT | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.