Recombinant Human FHIT Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : The protein encoded by this gene is a P1-P3-bis(5′-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 16.9 kDa | AA Sequence : MSFRFGQHLIKPSVVFLKTELSFAL VNRKPVVPGHVLVCPLRPVERFHDL RPDEVADLFQTTQRVGTVVEKHFHG TSLTFSMQDGPEAGQTVKHVHVHVL PRKAGDFHRNDSIYEELQKHDKEDF PASWRSEEEMAAEAAALRVYFQTRT RPLEQKLISEEDLAANDILDYKDDD DKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.