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Name :
Recombinant Human Fibroblast Growth Factor Receptor 2

Specification :
| Cat. No. : FGFR2-488H | Description : FGFR2 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation. FGFR2 is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, and mutations in FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. FGFR2 is required for early postimplantation development between implantation and the formation of the egg cylinder. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass. | Source : Sf21 Insect Cells. | Molecular Weight : The predicted molecular weight of Recombinant Human FGF R2α (IIIb) is Mr 66 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100 kDa. | State Of Matter : Lyophilized. | Purity : > 90% by SDS Page and analyzed by silver stain. | Endotoxin : | Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information :
| Gene Name : FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ] | Synonyms : FGFR2; fibroblast growth factor receptor 2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FLJ98662; FGF receptor; OTTHUMP00000020624; OTTHUMP00000020626; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14; EC 2.7.10.1; Crouzon syndrome; Pfeiffer syndrome; craniofacial dysostosis 1; Jackson-Weiss syndrome; Keratinocyte growth factor receptor 2; K-SAM; CD332 antigen; BEK fibroblast growth factor receptor; FGF receptor | Gene ID : 2263 | mRNA Refseq : NM_000141 | Protein Refseq : NP_000132 | UniProt ID : P21802 | Chromosome Location : 10q25.3-q26 | MIM : 176943 | Pathway : Endocytosis; MAPK signaling pathway; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton | Function : ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; receptor activity; transferase activity

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors