Recombinant Human Fibroblast Growth Factor Receptor 3, His-tagged

Specification :
| Cat. No. : FGFR3-5419H | Description : FGFs comprise a family of atleast eighteen structurally realted proteins that are involved in a multitudeof physiological and pathological cellular processes, including cell growth,differentation, angiogenesis, wound healing and tumorgenesis. The biologicalactivities of the FGFs are mediated by a family if type I transmembranetyrosine kinases which undergo dimerization and autophosphorylation afterligand binding. | Source : Insect cells | Species : Human | MolecularWeight : 49.8 kDa | Form : Liquid in 50 mMTris, pH 7.5 + 100 mM NaCl + 0.2 mM EDTA + 0.05% Triton X-100 + 5 mM DTT +50% glycerol. | Purity : ≥ 90% as determinedby SDS-PAGE analysis | Specific Activity : 550 nmoleof phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of totalprotein at 30°C. Activity determined at a final protein concentration of 2μg/ml. | Storage : Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. | OfficialSymbol : FGFR3