Recombinant Human Fms-Related Tyrosine Kinase 3 | Cholesterol Absorption Inhibitors cholesterol-absorption.com

Name :
Recombinant Human Fms-Related Tyrosine Kinase 3

Specification :
| Cat. No. : FLT3-1225H | Description : FLT3 Ligand is expressed from human 293cells as a monomeric glycoprotein with an apparent MW 24 to 30 kDa. Thiscytokine is produced in a serum-free, chemically defined media. The molecularmass is a narrower range than reported when this cytokine is expressed ininsect Sf21 cells (17 to 30 kDa), emphasizing the difference in glycosylationin different expression systems. | Source : HEK 293 cells | Species : Human | MolecularWeight : 24 to 30 kDamonomer, glycosylated | Purity : > 95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue. | Endotoxin Level : Endotoxin Free | Biological Activity : 0.2 to 0.8 ng/mLED50 | Storage : The specificactivity was determined by the dose-dependent stimulation of theproliferation of the human acute myeloid leukemia cell line OCI-AML5.

Gene Information :
| Gene Name : FLT3 fms-related tyrosine kinase 3 [ Homosapiens ] | Official Symbol : FLT3 | Synonyms : FLT3; fms-related tyrosinekinase 3; FLK2; STK1; CD135; CD135 antigen; fetal liver kinase 2; FL cytokinereceptor; tal liver kinase 2; stem cell tyrosine kinase 1; FLT3 receptortyrosine kinase; tyrosine-protein kinase receptor FLT3; growth factorreceptor tyrosine kinase type III; C 2.7.10.1; OTTHUMP00000042340; fetalliver kinase 2 | Gene ID : 2322 | mRNA Refseq : NM_004119 | Protein Refseq : NP_004110 | MIM : 136351 | UniProt ID : P36888 | Chromosome Location : 13q12 | Pathway : Acute myeloidleukemia; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage;Pathways in cancer | Function : ATP binding; nucleotidebinding; osphoinositide 3-kinase binding; protein binding; receptor activity;transferase activity; vascular endothelial growth factor receptor activity

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Author: Cholesterol Absorption Inhibitors

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