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Name :
Recombinant Human Fms-related Tyrosine Kinase 3

Specification :
| Cat. No. : FLT3-494H | Description : Fms-Like tyrosine kinase 3 (FLT3) is a member of the class III tyrosine kinase receptor family, normally expressed in hematopoietic, immune and neural systems. FLT3 is expressed in various lymphohematopoietic cells and tissues, including a series of immature cell lines and leukemias of lymphocytic origin. FLT3 is a promising target for the therapeutic intervention for acute leukemias, particularly acute myeloid leukemia (AML) which are severe and aggressive malignancy. | Molecular Weight : The predicted molecular weight of Recombinant Human Flt-3 is Mr 85.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 120 kDa. | Source : Mammalian cells | State Of Matter : Lyophilized. | Purity : >97% by SDS Page and analyzed by silver stain. | Endotoxin : | Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information :
| Gene Name : FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ] | Synonyms : FLT3; fms-related tyrosine kinase 3; FLK2; STK1; CD135; FLT3; CD135 antigen; FL cytokine receptor; fetal liver kinase 2; stem cell tyrosine kinase 1; FLT3 receptor tyrosine kinase; tyrosine-protein kinase receptor FLT3; growth factor receptor tyrosine kinase type III | Gene ID : 2322 | mRNA Refseq : NM_004119 | Protein Refseq : NP_004110 | MIM : 136351 | UniProt ID : P36888 | Chromosome Location : 13q12 | Pathway : Cytokine-cytokine receptor interaction; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Pathways in cancer | Function : ATP binding; nucleotide binding; phosphoinositide 3-kinase binding; protein binding; receptor activity; transferase activity; vascular endothelial growth factor receptor activity

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Author: Cholesterol Absorption Inhibitors