Recombinant Human FZD4 Protein, Fc-tagged

Specification :
| Description : This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. | Source : HEK293 | Species : Human | Tag : Fc | Form : Lyophilized | Molecular Mass : 42.9 kDa | Protein Length : 537 | AA Sequence : MAWRGAGPSVPGAPGGVGLSLGLLL QLLLLLGPARGFGDEEERRCDPIRI SMCQNLGYNVTKMPNLVGHELQTDA ELQLTTFTPLIQYGCSSQLQFFLCS VYVPMCTEKINIPIGPCGGMCLSVK RRCEPVLKEFGFAWPESLNCSKFPP QNDHNHMCMEGPGDEEVPLPHKTPI QPGEECHSVGTNSDQYIWVKRSLNC VLKCGYDAGLYSRSAKEFTDIWMAV WASLCFISTAFTVLTFLIDSSRFSY PERPIIFLSMCYNIYSIAYIVRLTV GRERISCDFEEAAEPVLIQEGLKNT GCAIIFLLMYFFGMASSIWWVILTL TWFLAAGLKWGHEAIEMHSSYFHIA AWAIPAVKTIVILIMRLVDADELTG LCYVGNQNLDALTGFVVAPLFTYLV IGTLFIAAGLVALFKIRSNLQKDGT KTDKLERLMVKIGVFSVLYTVPATC VIACYFYEISNWALFRYSADDSNMA VEMLKIFMSLLVGITSGMWIWSAKT LHTWQKCSNRLVNSGKVKREKRGNG WVKPGKGSETVV | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.