Name :
Recombinant Human GON7 Protein, Myc/DDK-tagged, C13 and N15-labeled
Specification :
| Description : Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit OSGEP in the complex. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 10.9 kDa | AA Sequence : MELLGEYVGQEGKPQKLRVSCEAPG DGDPFQGLLSGVAQMKDMVTELFDP LVQGEVQHRVAAAPDEDLDGDDEDD AEDENNIDNRTNFDGPSAKRPKTPS TRTRPLEQKLISEEDLAANDILDYK DDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Information :
| Gene Name : GON7 GON7 subunit of KEOPS complex [ Homo sapiens (human) ] | Official Symbol : GON7 | Synonyms : GON7; GON7 subunit of KEOPS complex; PNAS-127; C14orf142; EKC/KEOPS complex subunit GON7; GON7, KEOPS complex subunit homolog; uncharacterized protein C14orf142 | Gene ID : 84520 | mRNA Refseq : NM_032490 | Protein Refseq : NP_115879 | MIM : 617436 | UniProt ID : Q9BXV9
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