Name :
Recombinant Human GRK4 Protein, Myc/DDK-tagged, C13 and N15-labeled
Specification :
| Description : This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 66.6 kDa | AA Sequence : MELENIVANSLLLKARQGGYGKKSG RSKKWKEILTLPPVSQCSELRHSIE KDYSSLCDKQPIGRRLFRQFCDTKP TLKRHIEFLDAVAEYEVADDEDRSD CGLSILDRFFNDKLAAPLPEIPPDV VTECRLGLKEENPSKKAFEECTRVA HNYLRGEPFEEYQESSYFSQFLQWK WLERQPVTKNTFRHYRVLGKGGFGE VCACQVRATGKMYACKKLQKKRIKK RKGEAMALNEKRILEKVQSRFVVSL AYAYETKDALCLVLTIMNGGDLKFH IYNLGNPGFDEQRAVFYAAELCCGL EDLQRERIVYRDLKPENILLDDRGH IRISDLGLATEIPEGQRVRGRVGTV GYMAPEVVNNEKYTFSPDWWGLGCL IYEMIQGHSPFKKYKEKVKWEEVDQ RIKNDTEEYSEKFSEDAKSICRMLL TKNPSKRLGCRGEGAAGVKQHPVFK DINFRRLEANMLEPPFCPDPHAVYC KDVLDIEQFSAVKGIYLDTADEDFY ARFATGCVSIPWQNEMIESGCFKDI NKSESEEALPLDLDKNIHTPVSRPN RGFFYRLFRRGGCLTMVPSEKEVEP KQCTRTRPLEQKLISEEDLAANDIL DYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Information :
| Gene Name : GRK4 G protein-coupled receptor kinase 4 [ Homo sapiens (human) ] | Official Symbol : GRK4 | Synonyms : GRK4; G protein-coupled receptor kinase 4; G protein coupled receptor kinase 2 like (Drosophila), GPRK2L; GPRK4; ITI1; IT11; GRK4a; GPRK2L; | Gene ID : 2868 | mRNA Refseq : NM_182982 | Protein Refseq : NP_892027 | MIM : 137026 | UniProt ID : P32298
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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