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Name :
Recombinant Human GSK3A Protein, GST-tagged

Specification :
| Description : Glycogen synthase kinase 3-alpha (GSK3A; EC {2.7.1.37}) is a multifunctional protein serine kinase, homologous to Drosophila shaggy (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (see GYS1, {138570}) and transcription factors (e.g., JUN, {165160}). It also plays a role in the WNT ({164820}) and PI3K (see PIK3CG, {601232}) signaling pathways (see review by {1:Ali et al. (2001)}).[supplied by OMIM | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 77.4 kDa | AA Sequence : MSGGGPSGGGPGGSGRARTSSFAEP GGGGGGGGGGPGGSASGPGGTGGGK ASVGAMGGGVGASSSGGGPGGSGGG GSGGPGAGTSFPPPGVKLGRDSGKV TTVVATLGQGPERSQEVAYTDIKVI GNGSFGVVYQARLAETRELVAIKKV LQDKRFKNRELQIMRKLDHCNIVRL RYFFYSSGEKKDELYLNLVLEYVPE TVYRVARHFTKAKLTIPILYVKVYM YQLFRSLAYIHSQGVCHRDIKPQNL LVDPDTAVLKLCDFGSAKQLVRGEP NVSYICSRYYRAPELIFGATDYTSS IDVWSAGCVLAELLLGQPIFPGDSG VDQLVEIIKVLGTPTREQIREMNPN YTEFKFPQIKAHPWTKVFKSRTPPE AIALCSSLLEYTPSSRLSPLEACAH SFFDELRCLGTQLPNNRPLPPLFNF SAGELSIQPSLNAILIPPHLRSPAG TTTLTPSSQALTETPTSSDWQSTDA TPTLTNSS | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : GSK3A glycogen synthase kinase 3 alpha [ Homo sapiens ] | Official Symbol : GSK3A | Synonyms : GSK3A; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A; DKFZp686D0638; | Gene ID : 2931 | mRNA Refseq : NM_019884 | Protein Refseq : NP_063937 | MIM : 606784 | UniProt ID : P49840

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Author: Cholesterol Absorption Inhibitors