Name :
Recombinant Human GSK3B Protein, MYC/DDK-tagged, C13 and N15-labeled
Specification :
| Description : The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 47.9 kDa | AA Sequence : MSGRPRTTSFAESCKPVQQPSAFGS MKVSRDKDGSKVTTVVATPGQGPDR PQEVSYTDTKVIGNGSFGVVYQAKL CDSGELVAIKKVLQDKRFKNRELQI MRKLDHCNIVRLRYFFYSSGEKKDE VYLNLVLDYVPETVYRVARHYSRAK QTLPVIYVKLYMYQLFRSLAYIHSF GICHRDIKPQNLLLDPDTAVLKLCD FGSAKQLVRGEPNVSYICSRYYRAP ELIFGATDYTSSIDVWSAGCVLAEL LLGQPIFPGDSGVDQLVEIIKVLGT PTREQIREMNPNYTEFKFPQIKAHP WTKDSSGTGHFTSGVRVFRPRTPPE AIALCSRLLEYTPTARLTPLEACAH SFFDELRDPNVKLPNGRDTPALFNF TTQELSSNPPLATILIPPHARIQAA ASTPTNATAASDANTGDRGQTNNAA SASASNSTTRTRPLEQKLISEEDLA ANDILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Information :
| Gene Name : GSK3B glycogen synthase kinase 3 beta [ Homo sapiens (human) ] | Official Symbol : GSK3B | Synonyms : GSK3B; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform; glycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B; EC 2.7.11.1; EC 2.7.11.26 | Gene ID : 2932 | mRNA Refseq : NM_002093 | Protein Refseq : NP_002084 | MIM : 605004 | UniProt ID : P49841
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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