Name :
Active Recombinant Human FGFR3, Fc Chimera
Specification :
| Source : Mammalian cells | Species : Human | Tag : Fc Chimera | Predicted N Terminal : Glu23 | Form : Lyophilized from a 0.2 µm filtered solution in PBS. | Bio-activity : Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells.The ED50 for this effect is typically 0.03 – 0.12 µg/mL. | Molecular Mass : Recombinant Human FGFR3, Fc Chimera has a calculated MW of 65 kDa (monomer). In SDS-PAGE migrates as 90-100 kDa, reducing conditions. | Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. | Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Information :
| Gene Name : FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ] | Official Symbol : FGFR3 | Synonyms : FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX; | Gene ID : 2261 | mRNA Refseq : NM_000142 | Protein Refseq : NP_000133 | MIM : 134934 | UniProt ID : P22607 | Chromosome Location : 4p16.3
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