Name :
Recombinant Human ICOS protein, His-Avi-tagged
Specification :
| Description : Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22um filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 16.7KDa. | Protein length : Glu21-Phe141 | Endotoxin : Less than 1EU per ug by the LAL method. | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Gene Information :
| Gene Name : ICOS inducible T cell costimulator [ Homo sapiens (human) ] | Official Symbol : ICOS | Synonyms : Activation-inducible lymphocyte immunomediatory molecule; AILIM; AILIMCD278; CD278 antigen; CD278; CRP-1; CVID1; ICOS; inducible costimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; MGC39850 | Gene ID : 29851 | mRNA Refseq : NM_012092.4 | Protein Refseq : NP_036224.1 | MIM : 604558 | UniProt ID : Q9Y6W8
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