Name :
Recombinant Human ICOSLG protein, His-Avi-tagged, Biotinylated
Specification :
| Description : B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22μm filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 29.5 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. | Protein length : Asp19-Ser258 | Endotoxin : Less than 0.05 EU per μg by the LAL method. | Purity : >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Gene Information :
| Gene Name : ICOSLG | Official Symbol : ICOSLG | Synonyms : CD275 antigen; CD275; B7H2; B7-H2; B7H2B7 homolog 2; B7-H2B7-related protein 1; B7RP-1; B7RP1B7-like protein Gl50; B7RP-1LICOS; GL50; GL50transmembrane protein B7-H2 ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell co-stimulator ligand; KIAA0653ICOS ligand | Gene ID : 23308 | mRNA Refseq : NM_001283050.2 | Protein Refseq : NP_001269979.1 | MIM : 605717 | UniProt ID : O75144
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