Product: TA303312ABCB5 antibody
Quantity: 0.1 mg
Synonyms: ATP-binding cassette sub-family B member 5
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype:
CAS NO: 1339058-04-6 Product: YL0919
Shipping to: Europe, USA/Canada
Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_848654.3 and NP_001157413.1.AA Sequence:C-QTQHRNTSKKAQGeneID:340273
Application: Peptide ELISA: 1/32000 (Detection Limit).Western Blot: 0.3-1.0 µg/ml. Approx 90kDa band observed in Human Skin lysates and in lysates of cell line A431.Flow Cytometry: This antibody has been successfully used in FC for Hep3B cells as described in Ref.2
Background: ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently
Concentration: 0.5 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris saline, pH~7.3 with 0.02% Sodium Azide and 0.5% BSA
Preservatives:
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody is expected to recognize both reported isoforms of Human ABCB5 (NP_848654.3 and NP_001157413.1)