Product: AM32030SU-NABCC6 / MRP6 antibody
Quantity: 1 ml
Synonyms: ARA, ATP-binding cassette sub-family C member 6, MOAT-E, Multi-specific organic anion transporter E, Multidrug resistance-associated protein 6
Presentation: Supernatant
Clonality: Monoclonal
Host: Rat
Isotype: IgG2a
CAS NO: 173529-10-7 Product: HMN-176
Shipping to: Worldwide
Immunogen: Bacterial fusion protein of Human MRP6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein.GeneID:368
Application: Western blotting: Use 1/20-1/50 dilution and HRP-anti-Rat-IgG. Flow Cytometry (optimal conditions still to be defined). Immunocytochemistry: Use 1/20-1/50 on Acetone Fixed Cytospin preparations. Immunohistochemistry on Frozen Sections: 1/20 on Acetone Fix
Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. Defects in ABCC6 are the cause of pseudoxanthoma elasticum (PXE) [MIM:264800]. PXE is a disorder characterized by calcification of elastic fibers i
Concentration: ~0.25 mg IgG/ml
Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Buffer System:
Preservatives: 0.09% Sodium Azide
State: Serum Free Culture SupernatantSupernatant
Specifictiy: This Monoclonal antibody clone M6II-7 reacts with MRP6, a 190-200 kD transmembrane protein that is related to the multidrug resistance related protein MRP. It did not cross-react with the Human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products.
