Product: AP08038PU-NABL1 / ABL2 pTyr393/439 antibody
Quantity: 0.1 ml
Synonyms: ABL1, ABL2, Abelson Murine Leukemia Viral Oncogene Homolog 1 antibody, Bcr/c abl oncogene protein antibody, JTK7, Transformation gene oncogene ABL antibody, bcr/abl, c-ABL, p150
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype:
CAS NO: 179068-02-1 Product: PHCCC
Shipping to: Worldwide
Immunogen: Synthetic phosphopeptide derived from human ABL1/2 around the phosphorylation site of Tyrosine 393/439 (D-T-Yp-T-A).GeneID:25
Application: Immunofluorescence: 1/100 – 1/200.Immunohistochemistry on Paraffin-Embedded Sections: 1/50 – 1/100.Western Blot: 1/500 – 1/1000; Incubate membrane with diluted antibody in 5% nonfat milk, 1X TBS, 0,1% Tween-20 at 4°C with gentle shaking, overnight.
Background: ABL1, an Abl type protein kinase, is associated with cell differentiation, cell division, cell adhesion and stress response. Kinase activity of nuclear ABL1 is mediated by retinoblastoma protein. Additionally, ABL1 has been shown to bind nuclear DNA, and
Concentration: 1.0 mg/ml
Storage: Store the antibody (in aliquots) at -20°C.Avoid repeated freezing and thawing.Shelf life: One year from despatch.
Buffer System: PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Preservatives:
State: Liquid purified IgG fractionAff – Purified
Specifictiy: ABL1/ABL2 antibody detects endogenous levels of ABL1/2 only when phosphorylated at Tyrosine 393/439.
