Product: AP08253PU-NAIRE / APECED (Internal) antibody
Quantity: 50 µg
Synonyms: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype: IgG
CAS NO: 645-43-2 Product: Guanethidine (sulfate)
Shipping to: Worldwide
Immunogen: Synthetic peptide corresponding to the Internal region of Human AIREAA Sequence:C-KDVDLSQPRKGRKPGeneID:326Remarks:Percent identity by BLAST analysis: Human, Gorilla, Rat, Horse, Dog, Hamster, Elephant (100%); Panda (93%); Monkey, Mouse, Bovine (86%)
Application: ELISA: 1/32000.Western Blot: 0.5-1 µg/ml.Immunohistochemistry on Paraffin sections: 2.5 µg/ml (Heat induced antigen retrieval is required).
Background: AIRE is a transcriptional regulator that is thought to be important in controlling tissue-specific expression of genes in the thymus. The precise function of the protein is not well defined. It contains zinc finger motifs and isoform 1 is localized to bot
Concentration: 0.5 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris Saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer
Preservatives:
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody recognizes Internal region of Apeced Protein (AIRE).
